Preheat the oven the 375ºF
Spray a baking dish or pan with non-stick cooking spray
Pound the chicken breasts into an even thickness and cut in half crosswise, if desired
In a medium bowl mix the mayonnaise, Worcestershire Sauce, Lemon Juice, Garlic Powder, Onion Powder, Salt and Pepper.
In another bowl, mix the Breadcrumbs, Italian Seasoning, Garlic Powder, Onion Powder, Salt and Pepper.
Coat each piece of chicken in the wet mixture followed by the breadcrumb mixture and place into the prepared dish.
Bake uncovered for 30-40 minutes until lightly browned and cooked through.
Serve with your favorite sides.